Ethnicity and long-term course and outcome of psychotic disorders in a UK sample: the ÆSOP-10 study

Change log
Morgan, C 
Fearon, P 
Lappin, J 
Heslin, M 
Donoghue, K 

Background The incidence of psychotic disorders is elevated in some minority ethnic populations. However, we know little about the outcome of psychoses in these populations.

Aims To investigate patterns and determinants of long-term course and outcome of psychoses by ethnic group following a first episode.

Method ÆSOP-10 is a 10-year follow-up of an ethnically diverse cohort of 532 individuals with first-episode psychosis identified in the UK. Information was collected, at baseline, on clinical presentation and neurodevelopmental and social factors and, at follow-up, on course and outcome.

Results There was evidence that, compared with White British, Black Caribbean patients experienced worse clinical, social and service use outcomes and Black African patients experienced worse social and service use outcomes. There was evidence that baseline social disadvantage contributed to these disparities.


These findings suggest ethnic disparities in the incidence of psychoses extend, for some groups, to worse outcomes in multiple domains.

Disease Progression, Ethnicity, Follow-Up Studies, Humans, Incidence, Patient Acceptance of Health Care, Patient Outcome Assessment, Psychotic Disorders, United Kingdom
Journal Title
British Journal of Psychiatry
Conference Name
Journal ISSN
Volume Title
The Royal College of Psychiatrists
Medical Research Council (G0600972)
This work was supported by UK Medical Research Council (Ref: G0500817) and the Department of Health via the National Institute for Health Research (NIHR) Specialist Biomedical Research Centre for Mental Health award to South London and Maudsley NHS Foundation Trust (SLaM) and the Institute of Psychiatry at King’s College London.