Stem Cell-Derived Dopamine Neurons: Will They Replace DBS as the Leading Neurosurgical Treatment for Parkinson's Disease?

The use of stem cell-derived dopamine neurons or deep brain stimulation (DBS) represents two alternative approaches to treat Parkinson's Disease. DBS is a widely used FDA-approved treatment and stem cell-derived dopamine neuron replacement has now evolved to the first in-human clinical trials. In this debate, we discuss which of these approaches will evolve to be the treatment of choice for Parkinsonian patients in the future.

Keywords

DBS, Stem cells, brain repair, dopamine neurons, Deep Brain Stimulation, Dopaminergic Neurons, Humans, Neurosurgical Procedures, Parkinson Disease, Stem Cells

Journal Title

J Parkinsons Dis

Journal ISSN

1877-7171
1877-718X

Volume Title

11

Publisher

SAGE Publications

Publisher DOI

https://doi.org/10.3233/JPD-219008

Rights and licensing

Sponsorship

Medical Research Council (MC_PC_17230)

Collections

University of Cambridge Research Outputs (Articles and Conferences)