Repository logo
 

Imaging biomarkers in neurodegeneration: current and future practices.

Published version
Peer-reviewed

Type

Article

Change log

Authors

Young, Peter NE 
Estarellas, Mar 
Coomans, Emma 
Srikrishna, Meera 
Beaumont, Helen 

Abstract

There is an increasing role for biological markers (biomarkers) in the understanding and diagnosis of neurodegenerative disorders. The application of imaging biomarkers specifically for the in vivo investigation of neurodegenerative disorders has increased substantially over the past decades and continues to provide further benefits both to the diagnosis and understanding of these diseases. This review forms part of a series of articles which stem from the University College London/University of Gothenburg course "Biomarkers in neurodegenerative diseases". In this review, we focus on neuroimaging, specifically positron emission tomography (PET) and magnetic resonance imaging (MRI), giving an overview of the current established practices clinically and in research as well as new techniques being developed. We will also discuss the use of machine learning (ML) techniques within these fields to provide additional insights to early diagnosis and multimodal analysis.

Description

Keywords

Alzheimer’s disease, MRI, Machine learning, Neurodegenerative diseases, Neuroimaging, PET, dementia, Alzheimer Disease, Biomarkers, Humans, Magnetic Resonance Imaging, Neuroimaging, Positron-Emission Tomography

Journal Title

Alzheimers Res Ther

Conference Name

Journal ISSN

1758-9193
1758-9193

Volume Title

12

Publisher

Springer Science and Business Media LLC