mtDNA mutations help support cancer cells.
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Peer-reviewed
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Abstract
Mitochondrial DNA damage, metabolic disruption and aging have all been associated with cancer. These three threads are now woven together to show that aging-associated somatic mutations to mitochondrial DNA alter mitochondrial serine metabolism to support cell transformation and colon-cancer development.
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Nat Cancer
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2662-1347
2662-1347
2662-1347
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1
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Springer Nature
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