Toward Improved Kidney Cancer Risk Prediction Using High-risk Genetic Variants and Polygenic Risk Scores.

Toward Improved Kidney Cancer Risk Prediction Using High-risk Genetic Variants and Polygenic Risk Scores.

Accepted version

Peer-reviewed

Repository URI

https://www.repository.cam.ac.uk/handle/1810/401849

Repository DOI

https://doi.org/10.17863/CAM.129456

Files

Primary Accepted version (63.81 KB) (Embargoed until: 2027-05-01)

Type

Authors

Whitworth, James

https://orcid.org/0000-0002-3682-2298

Abstract

In this month’s issue of European Urology Oncology, Wei and colleagues report assessment of a recently published polygenic risk score for kidney cancer and validation of previously known monogenic risk factors using two biobank-based datasets.

Keywords

32 Biomedical and Clinical Sciences, 3211 Oncology and Carcinogenesis, Human Genome, Genetics, Prevention, Kidney Disease, Cancer Genomics, Cancer, 2.1 Biological and endogenous factors, 4.1 Discovery and preclinical testing of markers and technologies, Cancer

Journal Title

Eur Urol Oncol

Journal ISSN

2588-9311
2588-9311

Publisher

Elsevier

Publisher DOI

https://doi.org/10.1016/j.euo.2026.04.015

Rights and licensing

Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)

Except where otherwised noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)

Sponsorship

BRC

Collections

University of Cambridge Research Outputs (Articles and Conferences)