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Copper-Catalyzed Diastereo-and Enantioselective Borylative Cyclization

Published version
Peer-reviewed

Type

Article

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Authors

Abstract

jats:pCopper-catalyzed enantioselective borylative cyclization with various electrophiles via difunctionalization of unsaturated hydrocarbons is a powerful tool for the generation of interesting boron-containing carbocycles and heterocycles processes involving a chiral organocopper intermediate. Alkenes, allenes, and alkynes are versatile and easily accessible substrates that can be subjected to a wide range of reactions to produce densely functionalized, enantioenriched products. In this chapter, I discuss copper-catalyzed alkenes, allenes, and alkynes borofunctionalization and enantioselective cyclization via chiral organocopper intermediate. Copper-catalyzed enantioselective borylative cyclization and regiodivergent functionalization of alkenes, allenes, and alkynes, as well as the current mechanistic understanding of such processes, are given special attention in this review.</jats:p>

Description

Keywords

copper catalysis, enantioselective, borylation, cyclization

Journal Title

Catalysts

Conference Name

Journal ISSN

2073-4344
2073-4344

Volume Title

12

Publisher

MDPI AG