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Cell-cell interactions in joint pain: rheumatoid arthritis and osteoarthritis.

Accepted version
Peer-reviewed

Type

Article

Change log

Authors

Pattison, Luke A 
Krock, Emerson 
Svensson, Camilla I 
Smith, Ewan St J 

Abstract

Rheumatoid and osteoarthritis are chronic conditions generating joint pain for which better management is required. We argue that a better understanding of the cell-to-cell interactions occurring within the joint will enhance mechanistic understanding of joint pain and could lead to new therapeutic avenues being explored.

Description

Keywords

Arthralgia, Arthritis, Rheumatoid, Cell Communication, Humans, Osteoarthritis

Journal Title

Pain

Conference Name

Journal ISSN

0304-3959
1872-6623

Volume Title

162

Publisher

Ovid Technologies (Wolters Kluwer Health)
Sponsorship
Arthritis Research UK (11600/21973)
Biotechnology and Biological Sciences Research Council (BB/M011194/1)
L.A.P. was supported by the University of Cambridge BBSRC Doctoral Training Programme (BB/M011194/1). E.K. acknowledges support from a Canadian Institutes of Health Research Fellowship (201910MFE-430366-253212) and an International Association for the Study of Pain John J. Bonica Fellowship. C.I.S. acknowledges support from the Swedish Research Council (542-2013-8373) and Knut and Alice Wallenberg Foundation (2018-0161). E.St.J.S acknowledges support from Versus Arthritis (RG 21973).