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Developmental Paths to Anxiety in an Autism-Enriched Infant Cohort: The Role of Temperamental Reactivity and Regulation

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Charman, Tony 
Pasco, Greg 
Carr, Ewan 
Johnson, Mark H. 


Abstract: The aim of this study was to explore the associations between temperamental reactivity and regulation and the emergence of anxiety traits in a longitudinal sample of infants enriched for later ASD. Parents of 143 infants who were at high- and low-risk for ASD rated their child’s temperament traits when they were 9, 15 and 24 months old; they rated anxiety and ASD traits when they were 36 months old. The findings suggest that behavioural inhibition may be an early predictor of later anxiety in children with and without ASD and that lower levels of effortful control in children who later develop ASD may contribute to the higher expression of anxiety within this population.


Funder: King's College London


Origina lPaper, Autism spectrum disorder, Anxiety, Temperament, Reactivity, Regulation, High-risk

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Journal of Autism and Developmental Disorders

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Springer US
UK Medical Research Council (G0701484)
Innovative Medicines Initiative Joint Undertaking (115300)
Innovative Medicines Initiative 2 Joint Undertaking (777394)