Histidine metabolism boosts cancer therapy.
Accepted version
Peer-reviewed
Repository URI
Repository DOI
Change log
Authors
Abstract
Clinical use of the anticancer drug methotrexate can be limited by its high toxicity. It emerges that a diet rich in the amino acid histidine increases the effectiveness of methotrexate treatment and lowers toxicity in mice.
Description
Keywords
Journal Title
Nature
Conference Name
Journal ISSN
0028-0836
1476-4687
1476-4687
Volume Title
559
Publisher
Springer Nature
Publisher DOI
Rights and licensing
Except where otherwised noted, this item's license is described as All rights reserved
Sponsorship
MRC (unknown)
Medical Research Council (MC_UU_12022/6)
Medical Research Council (MC_UU_12022/6)