This is the final version of the article. It was first available from PLOS via http://dx.doi.org/10.1371/journal.pcbi.1004669

The data are electroencephalograms of electrical brain activity recorded in 20 healthy participants who were given the sedative propofol. For each participant, there are 4 datasets each with approximately 7 minutes of 91-channel EEG at rest, recorded at baseline, during mild sedation, moderate sedation, and finally at recovery. The EEG data have been filtered between 0.5-45Hz, segmented into 10-second epochs, cleaned and preprocessed to remove artefact, and referenced to the average of all channels. The datasets are in EEGLAB format.

For each dataset, there is an entry in the MATLAB table stored in the file datainfo.mat included. This entry specifies, in order:

1. the name of the dataset

1. the level of sedation at which the dataset was acquired (1 = baseline, 2 = mild sedation, 3 = moderate sedation, 4 = recovery)

1. the concentration of propofol measured in blood plasma at that level (in microgram/litre)

1. the average reaction times measured in a speeded two-choice response task administered at that level (in milliseconds)

1. the number of correct responses in that task (out of a max of 40)