Raw or processed data derived from native mass spectrometry, ion–mobility spectrometry–mass spectrometry and HDX–MS experiments organized into 4 folders. Folder name: Excess CK2alpha • Raw data of native mass spectrometry experiments with excess CK2α • E.g. CK2alpha-0.40AA.raw • AA refers to ammonium acetate • Numbers refer to concentration of ammonium acetate Folder name: Excess CK2beta • Raw data of native mass spectrometry experiments with excess CK2β • E.g. CK2beta-0.20AA.raw • AA refers to ammonium acetate • Numbers refer to concentration of ammonium acetate Folder name: HDX • Processed HDX data using CK2α as search sequence Folder name: Ion mobility • Raw data of ion mobility experiments • E.g. AH-H7.raw • First identifier (e.g. AH) refers to protein • Second identifier (e.g. H7) refers to wave height • AH = alcohol dehydrogenase • AVD = avidin • CCA = concanavalin A • PK = pyruvate kinase

Folder name: Excess CK2alpha • Raw data of native mass spectrometry experiments with excess CK2α • E.g. CK2alpha-0.40AA.raw • AA refers to ammonium acetate • Numbers refer to concentration of ammonium acetate

Folder name: Excess CK2beta • Raw data of native mass spectrometry experiments with excess CK2β • E.g. CK2beta-0.20AA.raw • AA refers to ammonium acetate • Numbers refer to concentration of ammonium acetate

Folder name: HDX • Processed HDX data using CK2α as search sequence

Folder name: Ion mobility • Raw data of ion mobility experiments • E.g. AH-H7.raw • First identifier (e.g. AH) refers to protein • Second identifier (e.g. H7) refers to wave height • AH = alcohol dehydrogenase • AVD = avidin • CCA = concanavalin A • PK = pyruvate kinase