This readme file was generated on [2024-04-29] by Adrian Buehler

GENERAL INFORMATION

Data collected for the publication "In vivo assessment of deep vascular patterns in murine colitis using optoacoustic mesoscopic imaging":

Author Information Name: Adrian P. Regensburger ORCID: 0000-0001-8244-1261 Institution: Department of Pediatrics and Adolescent Medicine, Friedrich-Alexander-Universität Erlangen-Nürnberg Address: Loschgestraße 15, 91054 Erlangen, Germany Email: adrian.regensburger@uk-erlangen.de

Author Information Name: Sarah E. Bohndiek ORCID: 0000-0003-0371-8635 Institution: Department of Physics and CRUK Cambridge Institute, University of Cambridge Address: J Thomson Avenue, Cambridge CB3 0HE, United Kingdom Email: seb53@cam.ac.uk

Date of data collection: From 2022-03-23 to 2022-04-21

Geographic location of data collection: CRUK Cambridge Institute, University of Cambridge, UK

Information about funding sources that supported the collection of the data: Interdisciplinary Center for Clinical Research (IZKF) at the University Hospital of the Friedrich-Alexander-Universität (FAU) (J89) Else Kröner-Fresenius-Stiftung funded APR Cancer Research UK (C9545/A29580) funded EB, MEO, and SEB

SHARING/ACCESS INFORMATION

Licenses/restrictions placed on the data: CC BY

Links to publications that cite or use the data: https://linkprotect.cudasvc.com/url?a=https%3A%2F%2Fdoi.org%2F10.1002%2Fadvs.202300564&c=E,1,zGLTufTpWY7r1JvOOItUW6g10YhWLov8OeaLrkbBwf59kp350RI3a3b4zF9OMx5b-wdoxBw7A0gcwb0Ly19vTmP8-VZfrTBOEGEU7Tdfaz4u6A,,&typo=1

DATA & FILE OVERVIEW

File List (with dimensions): mild_0_00_i.tif (300, 600, 924 (XYZ)) mild_0_00_w.tif (300, 600, 924 (XYZ)) mild_0_09_i.tif (300, 600, 924 (XYZ)) mild_0_09_w.tif (300, 600, 924 (XYZ)) mild_1_00_i.tif (300, 600, 924 (XYZ)) mild_1_00_w.tif (300, 600, 924 (XYZ)) mild_1_09_i.tif (300, 600, 924 (XYZ)) mild_1_09_w.tif (300, 600, 924 (XYZ)) mild_2_00_i.tif (300, 600, 924 (XYZ)) mild_2_00_w.tif (300, 600, 924 (XYZ)) mild_2_09_i.tif (300, 600, 924 (XYZ)) mild_2_09_w.tif (300, 600, 924 (XYZ)) mild_3_00_i.tif (300, 600, 924 (XYZ)) mild_3_00_w.tif (300, 600, 924 (XYZ)) mild_3_09_i.tif (300, 600, 924 (XYZ)) mild_3_09_w.tif (300, 600, 924 (XYZ)) mild_4_00_i.tif (300, 600, 924 (XYZ)) mild_4_00_w.tif (300, 600, 924 (XYZ)) mild_4_09_i.tif (300, 600, 924 (XYZ)) mild_4_09_w.tif (300, 600, 924 (XYZ)) mild_5_00_i.tif (300, 600, 924 (XYZ)) mild_5_00_w.tif (300, 600, 924 (XYZ)) mild_5_09_i.tif (300, 600, 924 (XYZ)) mild_5_09_w.tif (300, 600, 924 (XYZ)) mild_6_00_i.tif (300, 600, 924 (XYZ)) mild_6_00_w.tif (300, 600, 924 (XYZ)) mild_6_09_i.tif (300, 600, 924 (XYZ)) mild_6_09_w.tif (300, 600, 924 (XYZ)) mild_7_00_i.tif (300, 600, 924 (XYZ)) mild_7_00_w.tif (300, 600, 924 (XYZ)) mild_7_09_i.tif (300, 600, 924 (XYZ)) mild_7_09_w.tif (300, 600, 924 (XYZ)) mild_8_00_i.tif (300, 600, 924 (XYZ)) mild_8_00_w.tif (300, 600, 924 (XYZ)) mild_8_09_i.tif (300, 600, 924 (XYZ)) mild_8_09_w.tif (300, 600, 924 (XYZ)) mild_9_00_i.tif (300, 600, 924 (XYZ)) mild_9_00_w.tif (300, 600, 924 (XYZ)) mild_9_09_i.tif (300, 600, 924 (XYZ)) mild_9_09_w.tif (300, 600, 924 (XYZ)) severe_0_00_i.tif (400, 600, 924 (XYZ)) severe_0_00_w.tif (400, 600, 924 (XYZ)) severe_0_07_i.tif (300, 600, 924 (XYZ)) severe_0_07_w.tif (300, 600, 924 (XYZ)) severe_0_21_i.tif (300, 600, 924 (XYZ)) severe_0_21_w.tif (300, 600, 924 (XYZ)) severe_0_28_i.tif (300, 600, 924 (XYZ)) severe_0_28_w.tif (300, 600, 924 (XYZ)) severe_1_00_i.tif (400, 600, 924 (XYZ)) severe_1_00_w.tif (400, 600, 924 (XYZ)) severe_1_07_i.tif (400, 600, 924 (XYZ)) severe_1_07_w.tif (400, 600, 924 (XYZ)) severe_1_21_i.tif (300, 600, 924 (XYZ)) severe_1_21_w.tif (300, 600, 924 (XYZ)) severe_1_28_i.tif (300, 600, 924 (XYZ)) severe_1_28_w.tif (300, 600, 924 (XYZ)) severe_2_00_i.tif (300, 600, 924 (XYZ)) severe_2_00_w.tif (300, 600, 924 (XYZ)) severe_2_07_i.tif (300, 600, 924 (XYZ)) severe_2_07_w.tif (300, 600, 924 (XYZ)) severe_2_21_i.tif (300, 600, 924 (XYZ)) severe_2_21_w.tif (300, 600, 924 (XYZ)) severe_2_28_i.tif (300, 600, 924 (XYZ)) severe_2_28_w.tif (300, 600, 924 (XYZ)) severe_3_00_i.tif (300, 600, 924 (XYZ)) severe_3_00_w.tif (300, 600, 924 (XYZ)) severe_3_07_i.tif (300, 600, 924 (XYZ)) severe_3_07_w.tif (300, 600, 924 (XYZ)) severe_3_21_i.tif (300, 600, 924 (XYZ)) severe_3_21_w.tif (300, 600, 924 (XYZ)) severe_3_28_i.tif (300, 600, 924 (XYZ)) severe_3_28_w.tif (300, 600, 924 (XYZ)) severe_4_00_i.tif (300, 600, 924 (XYZ)) severe_4_00_w.tif (300, 600, 924 (XYZ)) severe_4_07_i.tif (300, 600, 924 (XYZ)) severe_4_07_w.tif (300, 600, 924 (XYZ)) severe_4_21_i.tif (300, 600, 924 (XYZ)) severe_4_21_w.tif (300, 600, 924 (XYZ)) severe_4_28_i.tif (300, 600, 924 (XYZ)) severe_4_28_w.tif (300, 600, 924 (XYZ)) severe_5_00_i.tif (300, 600, 924 (XYZ)) severe_5_00_w.tif (300, 600, 924 (XYZ)) severe_5_07_w.tif (300, 600, 924 (XYZ)) severe_5_21_i.tif (300, 600, 924 (XYZ)) severe_5_21_w.tif (300, 600, 924 (XYZ)) severe_5_28_i.tif (300, 600, 924 (XYZ)) severe_5_28_w.tif (300, 600, 924 (XYZ)) severe_6_00_i.tif (300, 600, 924 (XYZ)) severe_6_00_w.tif (300, 600, 924 (XYZ)) severe_6_07_i.tif (300, 600, 924 (XYZ)) severe_6_07_w.tif (300, 600, 924 (XYZ)) severe_6_21_i.tif (300, 600, 924 (XYZ)) severe_6_21_w.tif (300, 600, 924 (XYZ)) severe_6_28_i.tif (300, 600, 924 (XYZ)) severe_6_28_w.tif (300, 600, 924 (XYZ)) severe_7_00_i.tif (300, 600, 924 (XYZ)) severe_7_00_w.tif (300, 600, 924 (XYZ)) severe_7_07_i.tif (300, 600, 924 (XYZ)) severe_7_07_w.tif (300, 600, 924 (XYZ)) severe_7_21_i.tif (300, 600, 924 (XYZ)) severe_7_21_w.tif (300, 600, 924 (XYZ)) severe_7_28_i.tif (300, 600, 924 (XYZ)) severe_7_28_w.tif (300, 600, 924 (XYZ)) severe_8_00_i.tif (300, 600, 924 (XYZ)) severe_8_00_w.tif (300, 600, 924 (XYZ)) severe_8_07_i.tif (300, 600, 924 (XYZ)) severe_8_07_w.tif (300, 600, 924 (XYZ)) severe_8_21_i.tif (300, 600, 924 (XYZ)) severe_8_21_w.tif (300, 600, 924 (XYZ)) severe_8_28_i.tif (300, 600, 924 (XYZ)) severe_8_28_w.tif (300, 600, 924 (XYZ)) severe_9_00_i.tif (300, 600, 924 (XYZ)) severe_9_00_w.tif (300, 600, 924 (XYZ)) severe_9_07_i.tif (300, 600, 924 (XYZ)) severe_9_07_w.tif (300, 600, 924 (XYZ)) severe_9_21_i.tif (300, 600, 924 (XYZ)) severe_9_21_w.tif (300, 600, 924 (XYZ)) sham_0_00_i.tif (300, 600, 924 (XYZ)) sham_0_00_w.tif (300, 600, 924 (XYZ)) sham_0_09_i.tif (300, 600, 924 (XYZ)) sham_0_09_w.tif (300, 600, 924 (XYZ)) sham_1_00_i.tif (300, 600, 924 (XYZ)) sham_1_00_w.tif (300, 600, 924 (XYZ)) sham_1_09_i.tif (300, 600, 924 (XYZ)) sham_1_09_w.tif (300, 600, 924 (XYZ)) sham_2_00_i.tif (300, 600, 924 (XYZ)) sham_2_00_w.tif (300, 600, 924 (XYZ)) sham_2_09_i.tif (300, 600, 924 (XYZ)) sham_2_09_w.tif (300, 600, 924 (XYZ)) sham_3_00_i.tif (300, 600, 924 (XYZ)) sham_3_00_w.tif (300, 600, 924 (XYZ)) sham_3_09_i.tif (300, 600, 924 (XYZ)) sham_3_09_w.tif (300, 600, 924 (XYZ)) sham_4_00_i.tif (300, 600, 924 (XYZ)) sham_4_00_w.tif (300, 600, 924 (XYZ)) sham_4_09_i.tif (300, 600, 924 (XYZ)) sham_4_09_w.tif (300, 600, 924 (XYZ))

Naming Convention: study_subjectID_day_contrast.tif Each subject of each study group (mild, severe, sham) was imaged twice, both without ("_w") and with ("_i") contrast inside the transrectal absorber guide (TAG).

Dataset Size: 18.6 GB

METHODOLOGICAL INFORMATION

The data was collected using Raster‐Scanning Optoacoustic Mesoscopy as described by Buehler, Adrian, et al. in "Transrectal Absorber Guide Raster‐Scanning Optoacoustic Mesoscopy for Label‐Free In Vivo Assessment of Colitis." Advanced Science 10.18 (2023): 2300564. Subsequently, the data underwent motion correction, band-pass filtering, and reconstruction.

Methods for further processing: Vascular network quantification: https://github.com/AdrianBuehler/TAG-RSOM-Vessel-Analysis

People involved with sample collection, processing, analysis and/or submission: Adrian Buehler, Emma L. Brown

DATA-SPECIFIC INFORMATION FOR: severe_9_28_i.tif Not available

DATA-SPECIFIC INFORMATION FOR: severe_9_28_w.tif Not available