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Continuous flow synthesis enabling reaction discovery.

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Peer-reviewed

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Abstract

This article defines the role that continuous flow chemistry can have in new reaction discovery, thereby creating molecular assembly opportunities beyond our current capabilities. Most notably the focus is based upon photochemical, electrochemical and temperature sensitive processes where continuous flow methods and machine assisted processing can have significant impact on chemical reactivity patterns. These flow chemical platforms are ideally placed to exploit future innovation in data acquisition, feed-back and control through artificial intelligence (AI) and machine learning (ML) techniques.

Description

Acknowledgements: J. G. acknowledges the Fundación Ramón Areces for a postdoctoral fellowship (BEVP33P01S12222). We wish to thank Science Foundation Ireland for supporting our research program through grants 12/RC2275_P2, 19/IFA/7420 and 20/FFP-P/8712. SVL was supported by the American Chemical Society through receipt of the Arthur C. Cope Award.

Journal Title

Chem Sci

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Journal ISSN

2041-6520
2041-6539

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Publisher

Royal Society of Chemistry (RSC)

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Except where otherwised noted, this item's license is described as http://creativecommons.org/licenses/by-nc/3.0/
Sponsorship
Science Foundation Ireland (12/RC2275_P2, 19/IFA/7420, 20/FFP-P/8712)
Fundación Ramón Areces (BEVP33P01S12222)