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Connectomics and the neural basis of behaviour.

Accepted version
Peer-reviewed

Type

Article

Change log

Authors

Galili, Dana S 
Jefferis, Gregory Sxe 
Mesquita da Costa, Marta  ORCID logo  https://orcid.org/0000-0001-5948-3092

Abstract

Methods to acquire and process synaptic-resolution electron-microscopy datasets have progressed very rapidly, allowing production and annotation of larger, more complete connectomes. More accurate neuronal matching techniques are enriching cell type data with gene expression, neuron activity, behaviour and developmental information, providing ways to test hypotheses of circuit function. In a variety of behaviours such as learned and innate olfaction, navigation and sexual behaviour, connectomics has already revealed interconnected modules with a hierarchical structure, recurrence and integration of sensory streams. Comparing individual connectomes to determine which circuit features are robust and which are variable is one key research area; new work in comparative connectomics across development, experience, sex and species will establish strong links between neuronal connectivity and brain function.

Description

For the purpose of open access, the authors have applied a Creative Commons Attribution (CC BY) licence to this Author Accepted Manuscript version.

Keywords

Animals, Connectome, Nervous System, Neurons, Smell

Journal Title

Curr Opin Insect Sci

Conference Name

Journal ISSN

2214-5745
2214-5753

Volume Title

Publisher

Elsevier BV
Sponsorship
Wellcome Trust (220343/Z/20/Z)