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Successful restoration of arteriovenous dialysis access patency after late intervention.


Type

Article

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Authors

El-Damanawi, Ragada 
Kershaw, Stephanie 
Campbell, Gary 
Hiemstra, Thomas F 

Abstract

BACKGROUND: Arteriovenous dialysis access may be lost due to stenosis and thrombosis. Patency may be restored by thrombectomy or thrombolysis, but this is often not undertaken when the presentation is delayed. The success rate of delayed intervention is largely unknown. METHODS: In this single-centre study, we identified all instances of arteriovenous vascular access (VA) failure treated with angioplasty, thrombectomy or thrombolysis between August 2010 and July 2013. Patency rates immediately after intervention, and after 3 months, were assessed using multilevel mixed effects logistic regression. RESULTS: Sixty failures occurred in 41 accesses (38 patients). The access age at failure was 495 (316-888) days. Intervention was carried out after >48 h in 19 failures (32%). Immediate patency was achieved in 46 failures, of which 32 remained patent after 3 months. Delaying intervention increased the likelihood of achieving immediate patency (OR 0.55, 95% CI 0.31-1.0, P = 0.05). Having lost arteriovenous accesses previously increased the risk of immediate failure (OR 4.0, 95% CI 1.07-14.95, P = 0.04). There was no association between failure-to-intervention-time and 3-month patency rates (P = 0.23). Effect estimates did not differ between arteriovenous fistulae and synthetic arteriovenous grafts. CONCLUSION: Delayed intervention for failed arteriovenous VA may result in superior early patency rates and yields equivalent 3-month patency rates.

Description

Keywords

arteriovenous, dialysis, fistula, salvage, thrombosis

Journal Title

Clin Kidney J

Conference Name

Journal ISSN

2048-8505
2048-8513

Volume Title

8

Publisher

Oxford University Press (OUP)