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Diazo group as a new chemical reporter for bioorthogonal labelling of biomolecules


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Authors

Josa-Culleré, L 
Wainman, YA 
Brindle, KM 
Leeper, FJ 

Abstract

Diazoacetyl groups undergo spontaneous cycloaddition with strained alkenes and alkynes and can be bioorthogonal reporter groups labelling proteins and glycans.

Description

Keywords

3405 Organic Chemistry, 34 Chemical Sciences

Journal Title

RSC Advances

Conference Name

Journal ISSN

2046-2069
2046-2069

Volume Title

4

Publisher

Royal Society of Chemistry (RSC)
Sponsorship
L.J.C. was in receipt of the scholarship La Caixa and Y.A.W. was recipient of Cancer Research UK funding.