Genomic Structure in Europeans dating back at least 36,200 years
Authors
Seguin-Orlando, Andaine
Korneliussen, Thorfinn S
Sikora, Martin
Malaspinas, Anna-Sapfo
Moltke, Ida
Albrechtsen, Anders
Ko, Amy
Margaryan, Ashot
Moiseyev, Vyacheslav
Goebel, Ted
Westaway, Michael
Lambert, David
Khartanovich, Valeri
Wall, Jeffrey D
Nielsen, Rasmus
Orlando, Ludovic
Publication Date
2014-11-06Journal Title
Science
ISSN
0036-8075
Publisher
American Association for the Advancement of Science
Volume
346
Pages
1113-1118
Language
English
Type
Article
Metadata
Show full item recordCitation
Seguin-Orlando, A., Korneliussen, T. S., Sikora, M., Malaspinas, A., Manica, A., Moltke, I., Albrechtsen, A., et al. (2014). Genomic Structure in Europeans dating back at least 36,200 years. Science, 346 1113-1118. https://doi.org/10.1126/science.aaa0114
Abstract
The origin of contemporary Europeans remains contentious. We obtain a genome sequence from Kostenki 14 in European Russia dating to 38,700-36,200 years ago, one of the oldest fossils of Anatomically Modern Humans from Europe. We find that K14 shares a close ancestry with the 24,000 year old Mal’ta boy from central Siberia, European Mesolithic hunter-gatherers, some contemporary western Siberians and many Europeans, but not eastern Asians. Additionally, the Kostenki 14 genome shows evidence of shared ancestry with a population basal to all Eurasians that also relates to later European Neolithic farmers. We find that Kostenki 14 contains more Neandertal DNA that is contained in longer tracts than present Europeans. Our findings reveal the timing of divergence of western Eurasians and East Asians to be >36,200 years ago, and that European genomic structure today dates back to the Upper Paleolithic and derives from a meta-population that at times stretched from Europe to central Asia.
Sponsorship
GeoGenetics members were supported by the Lundbeck Foundation and the Danish National Research Foundation (DNRF94). ASM was supported by the Swiss National Science Foundation (PBSKP3_143529). Research on the archaeological background by PRN was supported by a MC Career Integration Grant (322261).
Funder references
European Commission (322261)
Identifiers
External DOI: https://doi.org/10.1126/science.aaa0114
This record's URL: https://www.repository.cam.ac.uk/handle/1810/246496
Rights
Licence:
http://www.rioxx.net/licenses/all-rights-reserved