Biotechnological exploitation of microalgae
Zedler, Julie AZ
Rajakumar, Priscilla D
Ramos, Martinez Erick M
Jensen, Poul Erik
Exploitation of microalgae
Journal of Experimental Botany
Oxford University Press
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Gangl, D., Zedler, J. A., Rajakumar, P. D., Ramos, M. E. M., Riseley, A., Włodarczyk, A., Purton, S., et al. (2015). Biotechnological exploitation of microalgae. Journal of Experimental Botany, 66 6975-6990. https://doi.org/10.1093/jxb/erv426
Microalgae are a diverse group of single-cell photosynthetic organisms that include cyanobacteria and a wide range of eukaryotic algae. A number of microalgae contain high-value compounds such as oils, colorants and polysaccharides, which are used by the food additive, oil and cosmetic industries, among others. They offer the potential for rapid growth under photoautotrophic conditions, and they can grow in a wide range of habitats. More recently, the development of genetic tools means that a number of species can be transformed and hence used as cell factories for the production of high-value chemicals or recombinant proteins. In this article we review exploitation use of microalgae with a special emphasis on genetic engineering approaches to develop cell factories, and the use of synthetic ecology approaches to maximise productivity. We discuss the success stories in these areas, the hurdles that need to be overcome, and the potential for expanding the industry in general.
This work was supported by the People Programme (Marie Curie Actions) of the European Union's Seventh Framework Programme FP7/2007-2013/ under REA grant agreement n° 317184 and from “Plant Power: Light-Driven Synthesis of Complex Terpenoids Using Cytochromes P450” (12-131834) funded by the Danish Council for Strategic Research, Programme Commission on Strategic Growth Technologies (PEJ, CR). PDR was funded by the UK’s Commonwealth Scholarship Commission.
EC FP7 MC ITN (317184)
Biotechnology and Biological Sciences Research Council (BB/L002957/1)
External DOI: https://doi.org/10.1093/jxb/erv426
This record's URL: https://www.repository.cam.ac.uk/handle/1810/250520