Supporting data for a protocol paper "Adaptive study of IL-2 dose frequency on regulatory T cells in type 1 diabetes (DILfrequency): a mechanistic, non-randomised, repeat dose, open label, response-adaptive study", published in BMJ Open, repository URI - https://www.repository.cam.ac.uk/handle/1810/250599 . The data available is the pilot data shown in Figure 2, the clinical flow cytometry (FACS) assay used to ascertain the co-primary endpoints of the study. These endpoints are: the frequency of T regulatory cells (Tregs), CD25 expression on Tregs, and the frequency of autoreactive effector T lymphocytes (Teffs). As the data is indvidual-level human subject data, it cannot be hosted on an Open Data repository, but is instead available on completion of a licence at the authors' website - https://www-gene.cimr.cam.ac.uk/data/ . While the website should be checked for a more recent version, a representative licence (current at 30th September 2015) is available here.

This record is licensed under a JDRF/Wellcome Trust DIL Data Access Agreement licence.