A tale of two inositol trisphosphates.
Change log
Authors
Irvine, Robin
Abstract
Between spring 1982 and autumn 1984 the physiological role of Ins(1,4,5)P3 as a calcium-mobilizing second messenger was first suggested and then experimentally established. At the same time the unexpected complexity of inositide metabolism began to be exposed by the discovery of Ins(1,3,4)P3. This article recalls my entanglement with these two inositol phosphates.
Description
Keywords
calcium, inositol, inositol phosphates, inositol trisphosphate, Animals, History, 20th Century, History, 21st Century, Humans, Inositol 1,4,5-Trisphosphate, Inositol Phosphates
Journal Title
Biochem Soc Trans
Conference Name
Journal ISSN
0300-5127
1470-8752
1470-8752
Volume Title
44
Publisher
Portland Press Ltd.