A tale of two inositol trisphosphates
Biochemical Society Transactions
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Irvine, R. (2016). A tale of two inositol trisphosphates. Biochemical Society Transactions, 44 202-211. https://doi.org/10.1042/BST20150205
Between spring 1982 and autumn 1984 the physiological role of inositol 1,4,5-trisphosphate as a calcium-mobilising second messenger was first suggested and then experimentally established. At the same time the unexpected complexity of inositide metabolism began to be exposed by the discovery of inositol 1,3,4-trisphosphate. This article recalls my entanglement with these two inositol phosphates.
External DOI: https://doi.org/10.1042/BST20150205
This record's URL: https://www.repository.cam.ac.uk/handle/1810/252738