The role of habit in compulsivity
Gillian, Claire M
van, den Heuvel Odile A
van, Wingen Guido
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Gillian, C. M., Robbins, T. W., Sahakian, B. J., van, d. H. O. A., & van, W. G. (2015). The role of habit in compulsivity. European Neuropsychopharmacology, 26 828-840. https://doi.org/10.1016/j.euroneuro.2015.12.033
Compulsivity has been recently characterized as a manifestation of an imbalance between the brain’s goal-directed and habit-learning systems. Habits are perhaps the most fundamental building block of animal learning, and it is therefore unsurprising that there are multiple ways in which the development and execution of habits can be promoted/discouraged. Delineating these neurocognitive routes may be critical to understanding if and how habits contribute to the many faces of compulsivity observed across a range of psychiatric disorders. In this review, we distinguish the contribution of excessive stimulus-response habit learning from that of deficient goal-directed control over action and response inhibition, and discuss the role of stress and anxiety as likely contributors to the transition from goal-directed action to habit. To this end, behavioural, pharmacological, neurobiological and clinical evidence are synthesized and a hypothesis is formulated to capture how habits fit into a model of compulsivity as a trans-diagnostic psychiatric trait.
Compulsivity, Habit, Goal-directed, OCD, Learning
CM Gillan is supported by a Sir Henry Wellcome Postdoctoral Fellowship (101521/Z/12/Z).
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External DOI: https://doi.org/10.1016/j.euroneuro.2015.12.033
This record's URL: https://www.repository.cam.ac.uk/handle/1810/253114
Attribution 4.0 International, Attribution 4.0 International, Attribution 4.0 International, Attribution 4.0 International
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