Supporting data for the article "Fragment-based approaches to the development of Mycobacterium tuberculosis CYP121 inhibitors", published in the Journal of Medicinal Chemistry, 2016. LCMS, HRMS, IR and NMR spectra from the characterisation of compounds reported in the Experimental Methods section of the article are provided as PDFs. Isothermal titration calorimetry enthalpy plots and data fitting for compounds reported in Table 2 of the article are provided as PDFs. Data for human cytochrome P450 inhibition studies with compounds 19a, 25a and 26a provided as a PDF.

This research data supports “Fragment-based approaches to the development of Mycobacterium tuberculosis CYP121 inhibitors” which will be published in “Journal of Medicinal Chemistry”.