The JAK-STAT signaling pathway is differentially activated in CALR-positive compared with JAK2V617F-positive ET patients.

Lau, Winnie WY; Hannah, Rebecca; Green, Anthony R; Göttgens, Bertie

The JAK-STAT signaling pathway is differentially activated in CALR-positive compared with JAK2V617F-positive ET patients.

Repository URI

https://www.repository.cam.ac.uk/handle/1810/254339

Files

HEFCE Exception sheet.pdf (86.94 KB)

Type

Article

Authors

Lau, Winnie WY

https://orcid.org/0000-0003-1209-1854

Hannah, Rebecca

Green, Anthony R

Göttgens, Bertie

https://orcid.org/0000-0001-6302-5705

Keywords

Amino Acid Substitution, Calreticulin, Gene Ontology, Humans, Janus Kinase 2, Megakaryocytes, Mutant Proteins, Mutation, STAT Transcription Factors, Signal Transduction, Thrombocythemia, Essential

Journal Title

Blood

Journal ISSN

0006-4971
1528-0020

Volume Title

125

Publisher

American Society of Hematology

Publisher DOI

https://doi.org/10.1182/blood-2014-12-618074

Rights

http://www.rioxx.net/licenses/all-rights-reserved

Sponsorship

Cancer Research Uk (None)
Biotechnology and Biological Sciences Research Council (BB/I00050X/1)
Leukaemia & Lymphoma Research (12029)
Wellcome Trust (097922/Z/11/Z)
Medical Research Council (MC_PC_12009)
Leukemia & Lymphoma Society (7001-12)
Wellcome Trust (097922/Z/11/B)

Collections

Scholarly Works - Wellcome-MRC Cambridge Stem Cell Institute
Symplectic mapped items for data match