Standardized Welfare Terms for the Zebrafish Community
Karp, Natasha A.
Murray, Katrina N.
Mary Ann Liebert
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Goodwin, N., Karp, N. A., Blackledge, S., Clark, B., Keeble, R., Kovacs, C., Murray, K. N., et al. (2016). Standardized Welfare Terms for the Zebrafish Community. Zebrafish, 13 (S1. S-164-S-168)https://doi.org/10.1089/zeb.2016.1248
This is the final version of the article. It first appeared from Mary Ann Liebert via https://doi.org/10.1089/zeb.2016.1248
Managing the welfare of laboratory animals is critical to animal health, vital in the understanding of phenotypes created by treatment or genetic alteration and ensures compliance of regulations. Part of an animal welfare assessment is the requirement to record observations, ensuring all those responsible for the animals are aware of their health status and can act accordingly. Although the use of zebrafish in research continues to increase, guidelines for conducting welfare assessments and the reporting of observations are considered unclear compared to mammalian species. To support the movement of zebrafish between facilities, significant improvement would be achieved through the use of standardized terms to ensure clarity and consistency between facilities. Improving the clarity of terminology around welfare not only addresses our ethical obligation but also supports the research goals and provides a searchable description of the phenotypes. A Collaboration between the Wellcome Trust Sanger Institute and Cambridge University (Department of Medicine-Laboratory of Molecular Biology) has led to the creation of the zebrafish welfare terms from which standardization of terminology can be achieved.
zebrafish, welfare, model organisms
This work was supported by the Wellcome Trust (grant no. 098051), the National Institutes of Health Office of Research Infrastructure Programs award (P40OD011021), the National Institutes of Health (grant no. A154503), National Institutes for Health Research to the Biomedical Research Centre (grant no. RG64229), and a Wellcome Trust Personal Research Fellowship (103950/Z/14/Z).
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External DOI: https://doi.org/10.1089/zeb.2016.1248
This record's URL: https://www.repository.cam.ac.uk/handle/1810/254567
Attribution 4.0 International
Licence URL: http://creativecommons.org/licenses/by/4.0/