Influenza Research Database: An integrated bioinformatics resource for influenza virus research
Nucleic Acids Research
Oxford University Press
MetadataShow full item record
Zhang, Y., Aevermann, B., Anderson, T., Burke, D., Dauphin, G., Gu, Z., He, S., et al. (2017). Influenza Research Database: An integrated bioinformatics resource for influenza virus research. Nucleic Acids Research, 45 (D1), D466-D474. https://doi.org/10.1093/nar/gkw857
The Influenza Research Database (IRD) is a U.S. National Institute of Allergy and Infectious Diseases (NIAID)-sponsored Bioinformatics Resource Center dedicated to providing bioinformatics support for influenza virus research. IRD facilitates the research and development of vaccines, diagnostics and therapeutics against influenza virus by providing a comprehensive collection of influenza-related data integrated from various sources, a growing suite of analysis and visualization tools for data mining and hypothesis generation, personal workbench spaces for data storage and sharing, and active user community support. Here, we describe the recent improvements in IRD including the use of cloud and high performance computing resources, analysis and visualization of user-provided sequence data with associated metadata, predictions of novel variant proteins, annotations of phenotype-associated sequence markers and their predicted phenotypic effects, hemagglutinin (HA) clade classifications, an automated tool for HA subtype numbering conversion, linkouts to disease event data and the addition of host factor and antiviral drug components. All data and tools are freely available without restriction from the IRD website at https://www.fludb.org.
National Institutes of Health/National Institute for Allergy and Infectious Diseases [HHSN272201400028C]. Funding for open access charge: J. Craig Venter Institute.
National Institutes of Health (NIH) (via Mount Sinai School of Medicine (MSSM)) (0258-0513/HHSN272201400008C)
Embargo Lift Date
External DOI: https://doi.org/10.1093/nar/gkw857
This record's URL: https://www.repository.cam.ac.uk/handle/1810/261986
Attribution 4.0 International, Attribution 4.0 International, Attribution 4.0 International, Attribution 4.0 International