Differential regenerative ability of sensory and motor neurons.

Cheah, Menghon; Fawcett, James W; Haenzi, Barbara

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Authors

Cheah, Menghon

Fawcett, James W

Haenzi, Barbara

Publication Date

2017-06-23

Journal Title

Neurosci Lett

ISSN

0304-3940

Publisher

Elsevier BV

Volume

652

Pages

35-40

Language

English

Type

Article

This Version

Physical Medium

Print-Electronic

Metadata

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Citation

Cheah, M., Fawcett, J. W., & Haenzi, B. (2017). Differential regenerative ability of sensory and motor neurons.. Neurosci Lett, 652 35-40. https://doi.org/10.1016/j.neulet.2016.11.004

Abstract

After injury, the adult mammalian central nervous system (CNS) lacks long-distance axon regeneration. This review discusses the similarities and differences of sensory and motor neurons, seeking to understand how to achieve functional sensory and motor regeneration. As these two types of neurons respond differently to axotomy, growth environment and treatment, the future challenge will be on how to achieve full recovery in a way that allows regeneration of both types of fibres simultaneously.

Sponsorship

This work was supported by grants from the Christopher and Dana Reeve Foundation, the Medical Research Council, the European Research Council ECMneuro, the Cambridge NHMRC Biomedical Research Centre.

Funder references

Medical Research Council (MR/R004544/1)

Identifiers

External DOI: https://doi.org/10.1016/j.neulet.2016.11.004

This record's URL: https://www.repository.cam.ac.uk/handle/1810/262069

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