Differential regenerative ability of sensory and motor neurons.
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Publication Date
2017-06-23Journal Title
Neurosci Lett
ISSN
0304-3940
Publisher
Elsevier BV
Volume
652
Pages
35-40
Language
English
Type
Article
This Version
AM
Physical Medium
Print-Electronic
Metadata
Show full item recordCitation
Cheah, M., Fawcett, J. W., & Haenzi, B. (2017). Differential regenerative ability of sensory and motor neurons.. Neurosci Lett, 652 35-40. https://doi.org/10.1016/j.neulet.2016.11.004
Abstract
After injury, the adult mammalian central nervous system (CNS) lacks long-distance axon regeneration. This review discusses the similarities and differences of sensory and motor neurons, seeking to understand how to achieve functional sensory and motor regeneration. As these two types of neurons respond differently to axotomy, growth environment and treatment, the future challenge will be on how to achieve full recovery in a way that allows regeneration of both types of fibres simultaneously.
Sponsorship
This work was supported by grants from the Christopher and Dana Reeve Foundation, the Medical Research Council, the European Research Council ECMneuro, the Cambridge NHMRC Biomedical Research Centre.
Funder references
Medical Research Council (MR/R004544/1)
Identifiers
External DOI: https://doi.org/10.1016/j.neulet.2016.11.004
This record's URL: https://www.repository.cam.ac.uk/handle/1810/262069
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