The Concise Guide to PHARMACOLOGY 2015/16: Overview
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Authors
Alexander, SP
Kelly, E
Marrion, N
Peters, JA
Benson, HE
Faccenda, E
Pawson, AJ
Sharman, JL
Southan, C
Buneman, OP
Catterall, WA
Cidlowski, JA
Fabbro, D
Fan, G
McGrath, JC
Spedding, M
Davies, JA
CGTP Collaborators,
Publication Date
2015-12-09Journal Title
British Journal of Pharmacology
ISSN
0007-1188
Publisher
Wiley-Blackwell
Volume
172
Issue
24
Pages
5729-5743
Language
English
Type
Article
This Version
VoR
Metadata
Show full item recordCitation
Alexander, S., Kelly, E., Marrion, N., Peters, J., Benson, H., Faccenda, E., Pawson, A., et al. (2015). The Concise Guide to PHARMACOLOGY 2015/16: Overview. British Journal of Pharmacology, 172 (24), 5729-5743. https://doi.org/10.1111/bph.13347
Abstract
The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13347/full. This compilation of the major pharmacological targets is divided into eight areas of focus: G protein-coupled receptors, ligand-gated ion channels, voltage-gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The Concise Guide is published in landscape format in order to facilitate comparison of related targets. It is a condensed version of material contemporary to late 2015, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in the previous Guides to Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates.
Sponsorship
We are extremely grateful for the financial contributions from the British Pharmacological Society, the International Union of Basic and Clinical Pharmacology, the Wellcome Trust (099156/Z/12/Z]), which support the website.
Identifiers
External DOI: https://doi.org/10.1111/bph.13347
This record's URL: https://www.repository.cam.ac.uk/handle/1810/263554
Rights
Attribution 4.0 International, Attribution 4.0 International, Attribution 4.0 International, Attribution 4.0 International