Cost effectiveness of endosonography versus surgical staging in potentially resectable lung cancer: a health economics analysis of the ASTER trial from a European perspective.
Authors
Rintoul, Robert C
Glover, Matthew J
Hughes, Victoria
Tournoy, Kurt G
Dooms, Christophe
Annema, Jouke T
Sharples, Linda D
Publication Date
2014-07Journal Title
Thorax
ISSN
0040-6376
Publisher
BMJ
Volume
69
Issue
7
Pages
679-681
Language
eng
Type
Article
Physical Medium
Print-Electronic
Metadata
Show full item recordCitation
Rintoul, R. C., Glover, M. J., Jackson, C., Hughes, V., Tournoy, K. G., Dooms, C., Annema, J. T., & et al. (2014). Cost effectiveness of endosonography versus surgical staging in potentially resectable lung cancer: a health economics analysis of the ASTER trial from a European perspective.. Thorax, 69 (7), 679-681. https://doi.org/10.1136/thoraxjnl-2013-204374
Abstract
In the ASTER study, mediastinal staging was more accurate for patients randomised to combined endobronchial and endoscopic ultrasound, followed by surgical staging if endoscopy was negative, versus surgical staging alone. Here, we report survival, quality of life and cost effectiveness up to 6 months, for the UK, The Netherlands and Belgium, separately. Survival in the two arms of the study was similar. In all three countries, the endosonography strategy had slightly higher quality-adjusted life years over 6 months, and was cheaper. Therefore, based on clinical accuracy and cost effectiveness, we conclude that mediastinal staging should commence with endosonography.
Keywords
Bronchoscopy, Health Economist, Lung Cancer, Non-Small Cell Lung Cancer, Thoracic Surgery, Bayes Theorem, Belgium, Cost-Benefit Analysis, Endosonography, Female, Humans, Lung Neoplasms, Lymphatic Metastasis, Male, Neoplasm Staging, Netherlands, Pneumonectomy, Positron-Emission Tomography, Postoperative Complications, Prospective Studies, Quality of Life, Sensitivity and Specificity, Survival Rate, Tomography, X-Ray Computed, United Kingdom
Identifiers
External DOI: https://doi.org/10.1136/thoraxjnl-2013-204374
This record's URL: https://www.repository.cam.ac.uk/handle/1810/280206
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