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dc.contributor.authorBlanchard, Guy
dc.contributor.authorÉtienne, Jocelyn
dc.contributor.authorGorfinkiel, Nicole
dc.date.accessioned2018-10-08T14:25:18Z
dc.date.available2018-10-08T14:25:18Z
dc.date.issued2018-08
dc.identifier.issn0959-437X
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/283236
dc.description.abstractWe review recent developments in the understanding of the biomechanics of apicomedial actomyosin and how its contractility can tense and deform tissue. Myosin pulses are driven by a biochemical oscillator but how they are modulated by the mechanical context remains unclear. On the other hand, the emergence of tissue behaviour is highly dependent on the material properties of actin, on how strongly components are connected and on the influence of neighbouring tissues. We further review the use of constitutive equations in exploring the mechanics of epithelial apices dominated by apicomedial Myosin contractility.
dc.format.mediumPrint-Electronic
dc.languageeng
dc.publisherElsevier BV
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectEpithelium
dc.subjectHumans
dc.subjectActins
dc.subjectMyosins
dc.subjectActomyosin
dc.subjectBiomechanical Phenomena
dc.titleFrom pulsatile apicomedial contractility to effective epithelial mechanics.
dc.typeArticle
prism.endingPage87
prism.publicationDate2018
prism.publicationNameCurr Opin Genet Dev
prism.startingPage78
prism.volume51
dc.identifier.doi10.17863/CAM.30600
dcterms.dateAccepted2018-07-16
rioxxterms.versionofrecord10.1016/j.gde.2018.07.004
rioxxterms.versionAM
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.licenseref.startdate2018-08
dc.contributor.orcidBlanchard, Guy [0000-0002-3689-0522]
dc.identifier.eissn1879-0380
rioxxterms.typeJournal Article/Review
pubs.funder-project-idWellcome Trust (099234/Z/12/Z)
pubs.funder-project-idBiotechnology and Biological Sciences Research Council (BB/J010278/1)
rioxxterms.freetoread.startdate2019-08-01


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Attribution-NonCommercial-NoDerivatives 4.0 International
Except where otherwise noted, this item's licence is described as Attribution-NonCommercial-NoDerivatives 4.0 International