Different opinion on the reported role of Poldip2 and ACSM1 in a mammalian lipoic acid salvage pathway controlling HIF-1 activation.
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Peer-reviewed
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Abstract
Paredes et al recently described Poldip2 as a novel regulator of mitochondrial lipoylation through stabilisation of ACSM1 (1). We have several concerns with their proposed model based on the following reasons.
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Journal Title
Proc Natl Acad Sci U S A
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Journal ISSN
0027-8424
1091-6490
1091-6490
Volume Title
115
Publisher
Proceedings of the National Academy of Sciences
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Except where otherwised noted, this item's license is described as All rights reserved
Sponsorship
Wellcome Trust (102770/Z/13/Z)
Lister Institute of Preventive Medicine (unknown)
Wellcome Trust (205252/Z/16/Z)
Lister Institute of Preventive Medicine (unknown)
Wellcome Trust (205252/Z/16/Z)
Wellcome 102770/Z/13/Z and 205252/Z/16/Z
Lister Institute RG87950
