Triple-Indicator-Based Multidimensional Colorimetric Sensing Platform for Heavy Metal Ion Detections.
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Idros, N., & Chu, D. (2018). Triple-Indicator-Based Multidimensional Colorimetric Sensing Platform for Heavy Metal Ion Detections.. ACS sensors, 3 (9), 1756-1764. https://doi.org/10.1021/acssensors.8b00490
Heavy metals are highly toxic at trace levels and their pollution has shown great threat to the environment and public health worldwide where current detection methods require expensive instrumentation and laborious operation, which can only be accomplished in centralized laboratories. Herein, we report a low-cost, paper-based microfluidic analytical device (µPAD) for a facile, portable and disposable monitoring of mercury, lead, chromium, nickel, copper and iron ions. Triple indicators or ligands that contain ions or molecules are preloaded on the µPADs and upon addition of a metal ion, the colorimetric indicators will elicit colour changes observed by the naked eyes. The colour features were quantitatively analysed in a three-dimensional space of red, green and blue or the RGB-space using digital imaging and colour calibration techniques. The sensing platform offers higher accuracy for cross references, and is capable of simultaneous detection and discrimination of different metal ions in even real water samples. It demonstrates great potential for semi-quantitative and even qualitative analysis with a sensitivity below the safe limit concentrations, and a controlled error range.
Metals, Heavy, Indicators and Reagents, Water Pollutants, Chemical, Calibration, Microfluidic Analytical Techniques, Colorimetry, Color, Paper, Lab-On-A-Chip Devices, Drinking Water, Ponds, Waste Water, Proof of Concept Study
External DOI: https://doi.org/10.1021/acssensors.8b00490
This record's URL: https://www.repository.cam.ac.uk/handle/1810/285159