Visible-Light-Mediated Annulation of Electron-Rich Alkenes and Nitrogen-Centered Radicals from N-Sulfonylallylamines: Construction of Chloromethylated Pyrrolidine Derivatives.
Accepted version
Peer-reviewed
Repository URI
Repository DOI
Change log
Abstract
A visible-light-mediated annulation of N-sulfonylallylamines and olefins is reported. Rapid access to highly functionalized chloromethylated pyrrolidines can be achieved using mild conditions for the generation of nitrogen-centered radicals. Both a transition-metal-based catalyst and an organic dye can be used as photosensitizers with 0.5 mol % loading. The reaction was found to be applicable to a large variety of electron-rich and electron-neutral olefins.
Description
Journal Title
Journal of Organic Chemistry
Conference Name
Journal ISSN
1520-6904
1520-6904
1520-6904
Volume Title
82
Publisher
American Chemical Society (ACS)
Publisher DOI
Rights and licensing
Except where otherwised noted, this item's license is described as All rights reserved
Sponsorship
Engineering and Physical Sciences Research Council (EP/M004120/1)
Engineering and Physical Sciences Research Council (EP/K009494/1)
Engineering and Physical Sciences Research Council (EP/K009494/1)
This work was supported by a postdoctoral fellowship from Pfizer (L.C. and A.G.) and the EPSRC Grants EP/K009494/1 and EP/M004120/1 (S.V.L.).