Tackling the Ethical Challenges Associated with Premature Delivery of Stem Cell-Based Therapies: Report of a Focus Session at the ISSCR 2018 Annual Meeting
Authors
Publication Date
2018-11-13Journal Title
Stem Cell Reports
ISSN
2213-6711
Publisher
Elsevier
Volume
11
Issue
5
Pages
1021-1025
Type
Article
This Version
AM
Metadata
Show full item recordCitation
Barker, R. (2018). Tackling the Ethical Challenges Associated with Premature Delivery of Stem Cell-Based Therapies: Report of a Focus Session at the ISSCR 2018 Annual Meeting. Stem Cell Reports, 11 (5), 1021-1025. https://doi.org/10.1016/j.stemcr.2018.10.020
Abstract
Despite a lack of clear evidence of safety and efficacy developed under traditional clinical translation pathways for medical therapies, there has been a surge of unproven clinical uses of stem cell-based interventions, often enabled by businesses marketing these purported therapies directly to patients. This is made possible in part by the diverse regulatory and policy environments in different countries. While the desire of patients to access therapeutic interventions is completely understandable, many stand to be harmed by receiving interventions that have not been adequately tested. This possibility raises substantial ethical concerns and has the potential to diminish public trust in cellular therapies more generally, incur health care costs due to adverse events and derail research into regenerative medicines. Regulators, scientists, clinicians, professional societies and patient advocacy groups need to work collaboratively to articulate the legal and ethical expectations of stem cell-based therapies and create novel approaches to their development, translation, regulation and governance.
Sponsorship
None
Funder references
Medical Research Council (MC_PC_12009)
Embargo Lift Date
2100-01-01
Identifiers
External DOI: https://doi.org/10.1016/j.stemcr.2018.10.020
This record's URL: https://www.repository.cam.ac.uk/handle/1810/286883
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