Epidemiology of diabetes
Medicine (United Kingdom)
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Forouhi, N., & Wareham, N. (2019). Epidemiology of diabetes. Medicine (United Kingdom), 47 (1), 22-27. https://doi.org/10.1016/j.mpmed.2018.10.004
Abstract The rising disease burden of diabetes mellitus globally is a major public health priority, placing unsustainable demands on individuals, their carers, health systems and society. The latest estimates show that there was a global prevalence of 425 million people with diabetes in 2017, which is expected to rise to 629 million by 2045. This is fuelled by the global rise in the prevalence of obesity and unhealthy behaviours including poor diets and physical inactivity; these are in turn promoted by wider societal determinants, including changes in nutrition in a global context (the so-called ‘nutrition transition’). The aetiological classification of diabetes principally separates diabetes mellitus into two main types, type 1 and type 2, with type 2 diabetes accounting for most (>85%) of the total diabetes mellitus prevalence. Both of the common forms of diabetes can lead to multisystem complications of microvascular endpoints, including retinopathy, nephropathy and neuropathy, and macrovascular endpoints, including ischaemic heart disease, stroke and peripheral vascular disease. The aetiology of type 1 diabetes is still incompletely understood. The role of modifiable factors in the causation of type 2 diabetes is better understood, making prevention a realistic public health goal.
Acknowledgement NGF and NJW acknowledge support from the core Medical Research Council Epidemiology Unit Programmes (MC_UU_12015/5 and MC_UU_12015/1).
Medical Research Council (MC_UU_12015/5)
Medical Research Council (MC_UU_12015/1)
Department of Health (via National Institute for Health Research (NIHR)) (NF-SI-0617-10149)
External DOI: https://doi.org/10.1016/j.mpmed.2018.10.004
This record's URL: https://www.repository.cam.ac.uk/handle/1810/288314