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Are neuropsychiatric symptoms modifiable risk factors for cognitive decline in Alzheimer's disease and vascular dementia?

Accepted version
Peer-reviewed

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Type

Article

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Authors

O'Brien, John T 
Sahakian, Barbara J 

Abstract

Alzheimer's disease and vascular dementia are associated with overlapping symptoms of anxiety and depression. More accurate discrimination between emerging neuropsychiatric and cognitive symptoms would better assist illness detection. The potential for protection against cognitive decline and dementia following early identification and intervention of neuropsychiatric symptoms warrants investigation.

Description

Keywords

Dementia, anxiety, depression, neuropsychiatric symptoms, Alzheimer Disease, Anxiety, Cognitive Dysfunction, Dementia, Vascular, Humans, Neuropsychological Tests, Risk Factors

Journal Title

Br J Psychiatry

Conference Name

Journal ISSN

0007-1250
1472-1465

Volume Title

216

Publisher

Royal College of Psychiatrists

Rights

All rights reserved
Sponsorship
George Savulich is funded by grants from Eton College and the Wallitt Foundation and is supported by the Cambridge NIHR Biomedical Research Centre (BRC) Mental Health Theme and Cambridge NIHR BRC Neurodegeneration theme. Barbara Sahakian is funded by the NIHR Cambridge Biomedical Research Centre (Mental Health Theme).