Etiologic Classification Criteria of ARCO on Femoral Head Osteonecrosis Part 1: Glucocorticoid-Associated Osteonecrosis.
Jones, Lynne C
Cheng, Edward Y
Goodman, Stuart B
Lee, Hee Young
Lee, Mel S
Lee, Yun Jong
Mont, Michael A
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Yoon, B., Jones, L. C., Chen, C., Cheng, E. Y., Cui, Q., Drescher, W., Fukushima, W., et al. (2019). Etiologic Classification Criteria of ARCO on Femoral Head Osteonecrosis Part 1: Glucocorticoid-Associated Osteonecrosis.. J Arthroplasty, 34 (1), 163-168.e1. https://doi.org/10.1016/j.arth.2018.09.005
BACKGROUND: Glucocorticoid usage, a leading cause of osteonecrosis of the femoral head (ONFH), and its prevalence was reported in 25%-50% of non-traumatic ONFH patients. Nevertheless, there have been no unified criteria to classify glucocorticoid-associated ONFH (GA-ONFH). In 2015, the Association Research Circulation Osseous addressed the issue of developing a classification scheme. METHODS: In June 2017, a task force was set up to conduct a Delphi survey concerning ONFH. The task force invited 28 experts in osteonecrosis/bone circulation from 8 countries. Each round of the Delphi survey consists of questionnaires, analysis of replies, and feedback reports to the panel. After 3 rounds of the survey, the panel reached a consensus on the classification criteria. The response rates were 100% (Round 1), 96% (Round 2), and 100% (Round 3), respectively. RESULTS: The consensus on the classification criteria of GA-ONFH included the following: (1) patients should have a history of glucocorticoid use >2 g of prednisolone or its equivalent within a 3-month period; (2) osteonecrosis should be diagnosed within 2 years after glucocorticoid usage, and (3) patients should not have other risk factor(s) besides glucocorticoids. CONCLUSION: Association Research Circulation Osseous established classification criteria to standardize clinical studies concerning GA-ONFH.
Humans, Femur Head Necrosis, Prednisolone, Glucocorticoids, Risk Factors, Consensus, Internationality, Delphi Technique, Advisory Committees
External DOI: https://doi.org/10.1016/j.arth.2018.09.005
This record's URL: https://www.repository.cam.ac.uk/handle/1810/292432
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