Genome Sequencing of Polydrug-, Multidrug-, and Extensively Drug-Resistant Mycobacterium tuberculosis Strains from South India.
Published version
Peer-reviewed
Repository URI
Repository DOI
Change log
Authors
Shanmugam, Sivakumar
Kumar, Narender
Nair, Dina
Natrajan, Mohan
Tripathy, Srikanth Prasad
Abstract
The genomes of 16 clinical Mycobacterium tuberculosis isolates were subjected to whole-genome sequencing to identify mutations related to resistance to one or more anti-Mycobacterium drugs. The sequence data will help in understanding the genomic characteristics of M. tuberculosis isolates and their resistance mutations prevalent in South India.
Description
Keywords
3107 Microbiology, 31 Biological Sciences, 3102 Bioinformatics and Computational Biology, 3105 Genetics, Antimicrobial Resistance, Vaccine Related, Rare Diseases, Genetics, Prevention, Human Genome, Infectious Diseases, Biotechnology, Biodefense, Tuberculosis, Emerging Infectious Diseases, 2.2 Factors relating to the physical environment, 2.1 Biological and endogenous factors, 5 Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, 2 Aetiology, Infection, 3 Good Health and Well Being
Journal Title
Microbiology Resource Announcements
Conference Name
Journal ISSN
2576-098X
2576-098X
2576-098X
Volume Title
8
Publisher
American Society for Microbiology
Publisher DOI
Sponsorship
Medical Research Council (MR/N501864/1)
This publication presents research supported by the MRC-DBT-funded partnership between the National Institute for Research in Tuberculosis, Chennai, India (Indian Council of Medical Research, New Delhi 5/2-8/LDCE/2014 for S.K., Department of Biotechnology [BT/IN/DBT-MRC (UK)/12/SS/2015-2016] for D.N., M.N., S.P.T., S.S., and U.D.R.) and the University of Cambridge (UK Medical Research Council [MR/N501864/1] for N.K. and S.P.).