Enhanced β-adrenergic signalling underlies an age-dependent beneficial metabolic effect of PI3K p110α inactivation in adipose tissue.

Araiz, Caroline; Yan, Anqi; Bettedi, Lucia; Samuelson, Isabella; Virtue, Samuel; McGavigan, Anne K; Dani, Christian; Vidal-Puig, Antonio; Foukas, Lazaros C

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Authors

Araiz, Caroline

Yan, Anqi

Bettedi, Lucia

Samuelson, Isabella

Virtue, Samuel

McGavigan, Anne K

Dani, Christian

Publication Date

2019-04-04

Journal Title

Nature communications

ISSN

2041-1723

Volume

Issue

Pages

1546

Language

eng

Type

Article

This Version

VoR

Physical Medium

Electronic

Metadata

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Citation

Araiz, C., Yan, A., Bettedi, L., Samuelson, I., Virtue, S., McGavigan, A. K., Dani, C., et al. (2019). Enhanced β-adrenergic signalling underlies an age-dependent beneficial metabolic effect of PI3K p110α inactivation in adipose tissue.. Nature communications, 10 (1), 1546. https://doi.org/10.1038/s41467-019-09514-1

Keywords

Adipose Tissue, Animals, Mice, Transgenic, Insulin Resistance, Obesity, Age Factors, Signal Transduction, Class I Phosphatidylinositol 3-Kinases

Sponsorship

MRC (MC_UU_12012/5)

Wellcome Trust (100574/Z/12/Z)

MRC (G0600717B)

MRC (G0802051)

MRC (G0400192)

MRC (MC_UU_12012/2)

British Heart Foundation (RG/18/7/33636)

Identifiers

External DOI: https://doi.org/10.1038/s41467-019-09514-1

This record's URL: https://www.repository.cam.ac.uk/handle/1810/293771

Rights

Attribution 4.0 International

Licence URL: https://creativecommons.org/licenses/by/4.0/

Except where otherwise noted, this item's licence is described as Attribution 4.0 International