Can circulating microRNAs solve clinical dilemmas in testicular germ cell malignancy?
Nature reviews. Urology
Nature Publishing Group
MetadataShow full item record
Murray, M., & Coleman, N. (2019). Can circulating microRNAs solve clinical dilemmas in testicular germ cell malignancy?. Nature reviews. Urology, 16 (9), 505-506. https://doi.org/10.1038/s41585-019-0214-2
Current clinical issues in testicular germ cell tumour management include limited sensitivity and specificity of conventional biomarkers and, therefore, reliance on serial CT imaging in follow-up monitoring, as well as poor ability to risk stratify patients. Circulating microRNAs are likely to help overcome these challenges and, importantly, could offer cost savings to healthcare systems.
Humans, Neoplasms, Germ Cell and Embryonal, Testicular Neoplasms, Male, Circulating MicroRNA
The authors thank St. Baldrick’s Foundation (reference 358099) and the Isaac Newton Trust (reference 15.40f) for grant funding and are grateful for support from the Max Williamson Fund and from Christiane and Alan Hodson, in memory of their daughter Olivia.
Isaac Newton Trust (1540 (f))
St Baldrick's Foundation (via Dana-Farber Cancer Institute) (2015-0743)
External DOI: https://doi.org/10.1038/s41585-019-0214-2
This record's URL: https://www.repository.cam.ac.uk/handle/1810/294349
All rights reserved