A redox switch in angiotensinogen modulates angiotensin release.

Zhou, Aiwu; Carrell, Robin W; Murphy, Mike; Wei, Zhenquan; Yan, Yahui; Stanley, Peter LD; Stein, Penelope; Broughton Pipkin, Fiona; Read, Randy

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Authors

Zhou, Aiwu

Carrell, Robin W

Murphy, Mike

Wei, Zhenquan

Yan, Yahui

Stanley, Peter LD

Stein, Penelope

Publication Date

2010-11

Journal Title

Nature

ISSN

0028-0836

Volume

468

Issue

7320

Pages

108-111

Language

eng

Type

Article

This Version

Physical Medium

Print-Electronic

Metadata

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Citation

Zhou, A., Carrell, R. W., Murphy, M., Wei, Z., Yan, Y., Stanley, P. L., Stein, P., et al. (2010). A redox switch in angiotensinogen modulates angiotensin release.. Nature, 468 (7320), 108-111. https://doi.org/10.1038/nature09505

Keywords

Humans, Pre-Eclampsia, Disulfides, Renin, Angiotensins, Angiotensinogen, Crystallography, X-Ray, Protein Processing, Post-Translational, Amino Acid Sequence, Protein Conformation, Oxidation-Reduction, Oxidative Stress, Pregnancy, Blood Pressure, Kinetics, Models, Molecular, Molecular Sequence Data, Female

Sponsorship

British Heart Foundation (PG/08/041/24818)

British Heart Foundation (PG/09/072/27945)

British Heart Foundation (BS/05/002/18361)

MRC (MC_U105663142)

Wellcome Trust (082961/Z/07/Z)

Identifiers

External DOI: https://doi.org/10.1038/nature09505

This record's URL: https://www.repository.cam.ac.uk/handle/1810/305243