SpatialDE: identification of spatially variable genes.
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Svensson, V., Teichmann, S., & Stegle, O. (2018). SpatialDE: identification of spatially variable genes.. Nature Methods, 15 (5), 343-346. https://doi.org/10.1038/nmeth.4636
Technological advances have made it possible to measure spatially resolved gene expression at high throughput. However, methods to analyze these data are not established. Here we describe SpatialDE, a statistical test to identify genes with spatial patterns of expression variation from multiplexed imaging or spatial RNA-sequencing data. SpatialDE also implements 'automatic expression histology', a spatial gene-clustering approach that enables expression-based tissue histology.
External DOI: https://doi.org/10.1038/nmeth.4636
This record's URL: https://www.repository.cam.ac.uk/handle/1810/307981
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