Elevated rates of autism, other neurodevelopmental and psychiatric diagnoses, and autistic traits in transgender and gender-diverse individuals.
Greenberg, David M
Springer Science and Business Media LLC
MetadataShow full item record
Warrier, V., Greenberg, D. M., Weir, E., Buckingham, C., Smith, P., Lai, M., Allison, C., & et al. (2020). Elevated rates of autism, other neurodevelopmental and psychiatric diagnoses, and autistic traits in transgender and gender-diverse individuals.. Nat Commun, 11 (1), 3959. https://doi.org/10.1038/s41467-020-17794-1
It is unclear whether transgender and gender-diverse individuals have elevated rates of autism diagnosis or traits related to autism compared to cisgender individuals in large non-clinic-based cohorts. To investigate this, we use five independently recruited cross-sectional datasets consisting of 641,860 individuals who completed information on gender, neurodevelopmental and psychiatric diagnoses including autism, and measures of traits related to autism (self-report measures of autistic traits, empathy, systemizing, and sensory sensitivity). Compared to cisgender individuals, transgender and gender-diverse individuals have, on average, higher rates of autism, other neurodevelopmental and psychiatric diagnoses. For both autistic and non-autistic individuals, transgender and gender-diverse individuals score, on average, higher on self-report measures of autistic traits, systemizing, and sensory sensitivity, and, on average, lower on self-report measures of empathy. The results may have clinical implications for improving access to mental health care and tailoring adequate support for transgender and gender-diverse individuals.
Humans, Confidence Intervals, Odds Ratio, Autistic Disorder, Adolescent, Adult, Aged, Aged, 80 and over, Middle Aged, Female, Male, Young Adult, Self Report, Transgender Persons
Wellcome Trust Templeton World Charity Foundation Autism Research Trust
Wellcome Trust (214322/Z/18/Z)
Autism Research Trust (unknown)
Embargo Lift Date
External DOI: https://doi.org/10.1038/s41467-020-17794-1
This record's URL: https://www.repository.cam.ac.uk/handle/1810/308050
All rights reserved