Amplification of actin polymerization forces.
Published version
Peer-reviewed
Repository URI
Repository DOI
Change log
Authors
Dmitrieff, Serge https://orcid.org/0000-0002-1362-5670
Nédélec, François
Abstract
The actin cytoskeleton drives many essential processes in vivo, using molecular motors and actin assembly as force generators. We discuss here the propagation of forces caused by actin polymerization, highlighting simple configurations where the force developed by the network can exceed the sum of the polymerization forces from all filaments.
Description
Keywords
Actin Cytoskeleton, Actins, Animals, Cell Movement, Humans, Mechanotransduction, Cellular, Models, Biological, Molecular Motor Proteins, Polymerization, Pseudopodia, Stress, Mechanical
Journal Title
J Cell Biol
Conference Name
Journal ISSN
0021-9525
1540-8140
1540-8140
Volume Title
212
Publisher
Rockefeller University Press