A CD8+ T cell transcription signature predicts prognosis in autoimmune disease.

McKinney, Eoin; Lyons, Paul; Carr, Edward; Hollis, Jane L; Jayne, David; Willcocks, Lisa C; Koukoulaki, Maria; Brazma, Alvis; Jovanovic, Vojislav; Kemeny, D Michael; Pollard, Andrew J; Macary, Paul A; Chaudhry, Afzal; Smith, Kenneth

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Authors

McKinney, Eoin

Lyons, Paul

Carr, Edward

Hollis, Jane L

Jayne, David

Willcocks, Lisa C

Koukoulaki, Maria

Publication Date

2010-05

Journal Title

Nature medicine

ISSN

1078-8956

Volume

Issue

Pages

586-591

Language

eng

Type

Article

This Version

Physical Medium

Print-Electronic

Metadata

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Citation

McKinney, E., Lyons, P., Carr, E., Hollis, J. L., Jayne, D., Willcocks, L. C., Koukoulaki, M., et al. (2010). A CD8+ T cell transcription signature predicts prognosis in autoimmune disease.. Nature medicine, 16 (5), 586-591. https://doi.org/10.1038/nm.2130

Keywords

T-Lymphocytes, CD8-Positive T-Lymphocytes, Humans, Vasculitis, Lupus Erythematosus, Systemic, Autoimmune Diseases, Inflammation, Receptors, Antigen, T-Cell, Immunosuppressive Agents, Antibodies, Antineutrophil Cytoplasmic, Interleukin-7, Prognosis, Cohort Studies, Signal Transduction, Autoimmunity, Gene Expression, Dose-Response Relationship, Drug

Sponsorship

Wellcome Trust (083650/Z/07/Z)

MRC (G0400929)

Wellcome Trust (079895/Z/06/B)

Wellcome Trust (079895/Z/06/A)

Identifiers

External DOI: https://doi.org/10.1038/nm.2130

This record's URL: https://www.repository.cam.ac.uk/handle/1810/313305