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Genomic Assemblies of Members of Burkholderia and Related Genera as a Resource for Natural Product Discovery.

Published version
Peer-reviewed

Repository URI

https://www.repository.cam.ac.uk/handle/1810/315228

Repository DOI

https://doi.org/10.17863/CAM.62333
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Published version (1.06 MB)

Type

Article

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Authors

Mullins, Alex J  ORCID logo  https://orcid.org/0000-0001-5804-9008
Jones, Cerith  ORCID logo  https://orcid.org/0000-0001-6275-0235
Webster, Gordon  ORCID logo  https://orcid.org/0000-0002-9530-7835
Parkhill, Julian  ORCID logo  https://orcid.org/0000-0002-7069-5958

Abstract

The genomes of 450 members of Burkholderiaceae, isolated from clinical and environmental sources, were sequenced and assembled as a resource for genome mining. Genomic analysis of the collection has enabled the identification of multiple metabolites and their biosynthetic gene clusters, including the antibiotics gladiolin, icosalide A, enacyloxin, and cepacin A.

Description

Keywords

3107 Microbiology, 31 Biological Sciences, 3105 Genetics, Human Genome, Biotechnology, Infectious Diseases, Genetics

Journal Title

Microbiol Resour Announc

Conference Name

Journal ISSN

2169-8287
2576-098X

Volume Title

9

Publisher

American Society for Microbiology

Publisher DOI

https://doi.org/10.1128/MRA.00485-20

Rights and licensing

Attribution 4.0 International
Except where otherwised noted, this item's license is described as Attribution 4.0 International
Sponsorship
Biotechnology and Biological Sciences Research Council (BB/L021692/1)

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University of Cambridge Research Outputs (Articles and Conferences)