A protocol for ultra-high field laminar fMRI in the human brain.
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Peer-reviewed
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Article
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Abstract
Ultra-high field (UHF) neuroimaging affords the sub-millimeter resolution that allows researchers to interrogate brain computations at a finer scale than that afforded by standard fMRI techniques. Here, we present a step-by-step protocol for using UHF imaging (Siemens Terra 7T scanner) to measure activity in the human brain. We outline how to preprocess the data using a pipeline that combines tools from SPM, FreeSurfer, ITK-SNAP, and BrainVoyager and correct for vasculature-related confounders to improve the spatial accuracy of the fMRI signal. For complete details on the use and execution of this protocol, please refer to Jia et al. (2020) and Zamboni et al. (2020).
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Keywords
Clinical Protocol, NMR, Neuroscience, Algorithms, Brain, Functional Neuroimaging, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Software
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STAR Protoc
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Journal ISSN
2666-1667
2666-1667
2666-1667
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2
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Elsevier BV
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Sponsorship
Wellcome Trust (205067/Z/16/Z)
Biotechnology and Biological Sciences Research Council (BB/P021255/1)
Medical Research Council (MR/M008983/1)
European Commission Horizon 2020 (H2020) Marie Sk?odowska-Curie actions (840271)
Wellcome Trust (098436/Z/12/B)
Biotechnology and Biological Sciences Research Council (BB/P021255/1)
Medical Research Council (MR/M008983/1)
European Commission Horizon 2020 (H2020) Marie Sk?odowska-Curie actions (840271)
Wellcome Trust (098436/Z/12/B)
This work was supported by grants to Z.K. from the Biotechnology and Biological Sciences Research Council (H012508 and BB/P021255/1), the Wellcome Trust (205067/Z/16/Z) and European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska Curie grant agreement No 840271.