Soft materials have found use in many areas such as medicine, robotics, and battery research. These advances are the result of the properties of gels stemming from both their solid- and liquid-like features. However, fine-tuning of these properties and an onset of new applications can be envisaged if gels are coupled to metal-organic cages (MOCs), discrete three-dimensional structures containing well-defined cavities. In this Perspective, we review the types of cage/gel smart materials synthesized until now, their properties, and potential applications such as molecular separations, catalysis, and luminescent materials. Finally, we highlight current challenges and opportunities for future research.