Sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting SARS-CoV-2 infection in schools, Austria, March 2021.
Published version
Peer-reviewed
Repository URI
Repository DOI
Change log
Authors
Willeit, Peter https://orcid.org/0000-0002-1866-7159
Bernar, Benoît
Zurl, Christoph
Al-Rawi, Mariam
Berghold, Andrea
Abstract
This study evaluates the performance of the antigen-based anterior nasal screening programme implemented in all Austrian schools to detect SARS-CoV-2 infections. We combined nationwide antigen-based screening data obtained in March 2021 from 5,370 schools (Grade 1-8) with an RT-qPCR-based prospective cohort study comprising a representative sample of 244 schools. Considering a range of assumptions, only a subset of infected individuals are detected with the programme (low to moderate sensitivity) and non-infected individuals mainly tested negative (very high specificity).
Description
Keywords
Antigen-based test, Children, PCR-based test, SARS-CoV-2, School, Sensitivity, Specificity, Austria, COVID-19, Humans, Prospective Studies, SARS-CoV-2, Schools, Self-Testing
Journal Title
Euro Surveill
Conference Name
Journal ISSN
1025-496X
1560-7917
1560-7917
Volume Title
26
Publisher
European Centre for Disease Control and Prevention (ECDC)