25 Years of Research in Human Lactation: From Discovery to Translation.
Geddes, Donna Tracy
Mitoulas, Leon Robert
Kent, Jacqueline Coral
Stinson, Lisa Faye
Hartmann, Peter Edwin
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Geddes, D. T., Gridneva, Z., Perrella, S. L., Mitoulas, L. R., Kent, J. C., Stinson, L. F., Lai, C. T., et al. (2021). 25 Years of Research in Human Lactation: From Discovery to Translation.. Nutrients, 13 (9) https://doi.org/10.3390/nu13093071
Researchers have recently called for human lactation research to be conceptualized as a biological framework where maternal and infant factors impacting human milk, in terms of composition, volume and energy content are studied along with relationships to infant growth, development and health. This approach allows for the development of evidence-based interventions that are more likely to support breastfeeding and lactation in pursuit of global breastfeeding goals. Here we summarize the seminal findings of our research programme using a biological systems approach traversing breast anatomy, milk secretion, physiology of milk removal with respect to breastfeeding and expression, milk composition and infant intake, and infant gastric emptying, culminating in the exploration of relationships with infant growth, development of body composition, and health. This approach has allowed the translation of the findings with respect to education, and clinical practice. It also sets a foundation for improved study design for future investigations in human lactation.
Breast, Lactation, Milk composition, Human Milk, Infant Feeding, Breastfeeding
Medela (University of Western Australia)
External DOI: https://doi.org/10.3390/nu13093071
This record's URL: https://www.repository.cam.ac.uk/handle/1810/330098
Attribution 4.0 International
Licence URL: https://creativecommons.org/licenses/by/4.0/