Advances in the Sensing and Treatment of Wound Biofilms.
Girault, Hubert H
Kaminski, Clemens F
Angew Chem Int Ed Engl
MetadataShow full item record
Darvishi, S., Tavakoli, S., Kharaziha, M., Girault, H. H., Kaminski, C. F., & Mela, I. (2021). Advances in the Sensing and Treatment of Wound Biofilms.. Angew Chem Int Ed Engl https://doi.org/10.1002/anie.202112218
Wound biofilms represent a particularly challenging problem in modern medicine. They are increasingly antibiotic resistant and can prevent the healing of chronic wounds. However, current treatment and diagnostic options are hampered by the complexity of the biofilm environment. In this review, we present new chemical avenues in biofilm sensors and new materials to treat wound biofilms, offering promise for better detection, chemical specificity, and biocompatibility. We briefly discuss existing methods for biofilm detection and focus on novel, sensor-based approaches that show promise for early, accurate detection of biofilm formation on wound sites and that can be translated to point-of-care settings. We then discuss technologies inspired by new materials for efficient biofilm eradication. We focus on ultrasound-induced microbubbles and nanomaterials that can both penetrate the biofilm and simultaneously carry active antimicrobials and discuss the benefits of those approaches in comparison to conventional methods.
Chronic wound biofilm, Detection, Therapy, Sensors, Nanotechnology
National Biofilms Innovation Centre (NBIC) (via University of Southampton) (BB/R012415/1 - 03PoC20-105)
External DOI: https://doi.org/10.1002/anie.202112218
This record's URL: https://www.repository.cam.ac.uk/handle/1810/331280
All Rights Reserved
Licence URL: http://www.rioxx.net/licenses/all-rights-reserved
Recommended or similar items
The current recommendation prototype on the Apollo Repository will be turned off on 03 February 2023. Although the pilot has been fruitful for both parties, the service provider IKVA is focusing on horizon scanning products and so the recommender service can no longer be supported. We recognise the importance of recommender services in supporting research discovery and are evaluating offerings from other service providers. If you would like to offer feedback on this decision please contact us on: firstname.lastname@example.org